ICIAM2019に参加・発表
2019年7月15日から2019年7月19日にスペイン・バレンシアにて開催されたICIAM2019に参加しました。
発表詳細
| Author(s): | Shoya Iwanami, Kosaku Kitagawa, Hirofumi Ohashi, Yusuke Asai, Koichi Watashi, Shingo Iwami |
| Title: | A quantitative comparison between hepatitis C virus JFH-1 and Jc1 by a PDE multiscale model of virus infection. |
| Conference: | 9th International Congress on Industrial and Applied Mathematics (ICIAM 2019) |
| Place: | Valencia, Spain |
| Date: | 2019年7月16日(火) |
Abstract
We developed a mathematical model of virus dynamics by partial differential equations which is multi-scale model to simultaneously describe intercellular virus infection and intracellular virus replication. We analyzed the experimental data of hepatitis C virus (HCV) JFH-1 and Jc1 infection in cell culture using the mathematical model and estimated parameters which described characteristics of HCV strains. As a result of comparison of estimated parameters, we found that JFH-1 strain had higher fitness than Jc1 strain.